Increasing prevalence of hepatic disease is likely to translate in a growing number
of patients with significant hepatic disease requiring cardiac surgery. Available
cardiac risk stratification models do not address the risk associated with hepatic
disease. However, weighted mean mortality rates based on previous studies of cardiac
surgery in patients with hepatic disease demonstrate operative mortality rates that
range from 9.88% (standard deviation [SD] 9.69) for patients in Child–Turcotte–Pugh
(CTP) class A cirrhosis to 69.23% (SD 28.55) for patients with CTP class C cirrhosis.
This review comprehensively appraises the pathophysiology of hepatic disease, reported
clinical outcomes and considerations for risk stratification.
Keywords
liver diseases/cirrhosis - risk - outcomes
